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Blood biomarkers of telltale signs of early Alzheimer’s disease in the brain of his patient, 55-year-old entrepreneur Simon Nicholls, had all but disappeared in a mere 14 months. “I don’t use the term ‘reverse.’ I don’t know what reverse means when it comes to the field of Alzheimer’s,” Isaacson said. ‘It was time to turn to my brain’Slowly, Nicholls’ heart condition began to improve, but the bad news didn’t end there. A brain scan found telltale signs of vascular damage in Nicholls’ brain, which occurs when the tiniest blood vessels are starved of oxygen. Not only was Nicholls blood negative for amyloid and tau, the test suggested that his brain amyloid might be normal, with no distinguishable signs of the disease.
Persons: Sanjay Gupta, Anderson Cooper ”, Richard Isaacson, Simon Nicholls, , , Isaacson, “ Simon, ” Isaacson, Nicholls, ” Nicholls, Anderson Cooper, It’s, APOE4, Simon, ” Simon Nicholls, Sylver, Lewy, Richard Isaacson ‘, APOE ε4, “ I’ve, Isaacson doesn’t, “ I’m, Shocked, Dr, we’d, “ It’s, Salvadore, Richard Isaacson “, ‘ It’s, I’m Organizations: CNN, telltale, ” CNN, Boca Raton Locations: Boca Raton , Florida, New York City, Florida, Nature, Miami, Isaacson’s Florida, tirzepatide
The middle class is more of a club than an income bracketThe ranks of middle-income earners have been shrinking, according to the Pew Research Center. A solid chunk of millionaires consider themselves middle class, despite accounting for just over 12% of American families. And there's good reasons," Lawrence R. Samuel, the author of the book "The American Middle Class: A Cultural History," told Business Insider. "Being middle class is almost like classless. Clinging to at least the mirage of the middle class might be important to upholding more core American ideals.
Persons: , they're, Claire Tassin, Tassin, they'd, ALICE, Amanda, She's, there's, Rakesh Kochhar, That's, Kochhar, Lawrence R, Samuel, we're Organizations: Service, Business, Pew Research, Pew Research Center Locations: America, Texas
There is an irony at the heart of the sports-as-entertainment business that most television executives would acknowledge but very few would ever publicly admit. It starts with a network’s committing billions of dollars for the rights to show the competition, and it builds from there. That can be doubled, at least, for a game on foreign soil, once hotels are reserved, equipment transported and flights booked. And then, of course, there is what is still called — though not always that accurately — the talent. A huge amount of time, thought and money goes into those segments: the fevered buildup, the halftime fat-chewing, the postgame bone picking.
Organizations: Broadcasting
Now, Zyn users are buzzing about another purported side effect: Some claim that their habit has triggered weight loss. Andrea Hernández, author of consumer trend newsletter Snaxshot, pointed out this craze this week, sharing a collection of social media posts about Zyn and weight loss. "I've used Zyn nicotine pouches occasionally over the past few years but have started to use them regularly because they help me focus and curb my hunger," a Reddit user wrote in r/intermittentfasting. While nicotine pouches circumvent the health effects of cigarettes that are caused by tobacco, they still do a number on your body. She worries that "we don't fully understand how nicotine works to regulate appetite in people, specifically with obesity."
Persons: , Tucker Carlson, Carlson, Andrea Hernández, I've, Carolyn Bramante, Bramante, vapes, Slim, Apple AirPods, Philip Morris, Forget, I'm, Elon Musk, Charles Barkley, Hernández, Michael M, Beverly Tchang, Tchang, Iuliia Burmistrova Organizations: Service, Business, University of Minnesota, FDA, Lucky, Samsung, Getty, Weill, Philip Morris International, Swedish Locations: New York
CNN —Eating a vegan, vegetarian or lacto-ovo vegetarian diet significantly reduces the overall risk of developing cancer, heart disease and dying early from cardiovascular disease, according to a new “umbrella” analysis of more than 20 years of research. “Plants have more fiber (animal foods have zero), less saturated fat and zero cholesterol (all animal foods have cholesterol),” Gardner said in an email. However, vegetarian diets limiting but not completely excluding certain types of meat and fish, such as pesco- or pollo-vegetarian diets, were excluded, he said. “Strictly vegan diets can be deficient in vitamin B12,” Gardner said. “Iron is another nutrient that is harder to get from a fully vegan diet,” Gardner added.
Persons: , Dr, Angelo Capodici, Federica, Guaraldi, David Katz, ” Katz, Christopher Gardner, Gardner, ” Gardner, , Davide Gori, ” Gori, It’s, Wesley Soares Ferracini Organizations: CNN, Scuola Superiore, IRCCS Institute of Neurological Sciences, True Health Initiative, Stanford Prevention Research Center, University of Bologna, Mayo Clinic, B12 Locations: Pisa, Italy, Bologna, Palo Alto , California
If you'd told me 10 years ago I'd feel ashamed of losing weight, I wouldn't have believed you. I've been on a roller coaster of body shame and acceptance since I was 12, which, at times, led to bouts of disordered eating. My primary doctor suggested I try a medical weight loss program, which involves seeing a nutritionist and weight loss doctor monthly, as well as prescription weight loss drugs. I've been scared because of the hurtful commentary and speculation I see online about others losing weight by taking medication. However, I am conscience-stricken for taking weight loss medicine when all I am trying to do is improve my health.
Persons: you'd, I've, I'd, I'm
Fat Brands announced its intention to spin off Twin Peaks through an IPO last year. Since its founding in 2005, Twin Peaks has grown to nearly 115 restaurant locations in the U.S. and Mexico. Smokey Bones is a newer addition to Fat Brands' portfolio, which currently includes 18 chains. Fat Brands acquired it in September 2023, with the goal of converting more than half of its 61 corporate-owned restaurants into Twin Peaks locations. Wiederhorn has a 45% stake in Fat Brands through Fog Cutter Holdings, according to FactSet.
Persons: Brands, Smokey, Andy Wiederhorn, Smokey Bones, Darden, Wiederhorn Organizations: Fat Brands, Securities and Exchange, Brands, SEC, Hooters, Olive Garden, Fog Cutter Locations: Wiederhorn, Los Angeles, U.S, Mexico, Olive, Twin
Foods rich in omega-3 fatty acids include salmon, sardines and various nuts including walnuts. Linoleic acid is the most common omega-6 fatty acid. Also, accurately measuring fatty acid intake is difficult, partly due to reliance on participants’ own recollections of their dietary intake. Considered individually, both high levels of omega-6 and omega-3 were linked with a lower risk of premature death. Some patients request it with the goal of improving their mental health, heart health or risk of dementia, she said.
Persons: , Yuchen Zhang, Zhang, chia, ” Zhang, Lauren R, Sastre, Sastre wasn’t, ” Sastre, Kristin Kirkpatrick, Kirkpatrick, , ” Kirkpatrick Organizations: CNN, University of Georgia’s College of Public Health, Omega, National Institutes of Health, Clinic Program, East Carolina University, Cleveland Clinic, Regenerative, Harvard Health Locations: United Kingdom
Guy Fieri has been building a healthy diet and fitness routine since 2020. His regular routine includes rucking, hiking with a weight vest uphill, he told Men's Health. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . Guy Fieri has lost more than 30 pounds in the past few years thanks to a healthy diet and dedicated workout routine, including HIIT classes, Men's Health reported. His new routine includes rucking, a fitness craze that has enthralled elites, from Silicon Valley to Hollywood.
Persons: Guy Fieri, Men's, It's, Organizations: Men's Health, Service, Health, Business Locations: Flavortown, Silicon Valley, Hollywood
Read previewA dietitian specializing in cancer prevention told Business Insider that simple lifestyle changes can be powerful when it comes to reducing the risk of developing cancer. The rates of younger adults being diagnosed with cancer have been rising since the '90s, according to the American Cancer Society, with colorectal, breast, and stomach cancers a particular concern. But certain lifestyle choices can help to prevent cancer, Tejal Parekh, a registered and licensed dietitian who specializes in helping mesothelioma patients reduce cancer symptoms through diet at Asbestos.com, told Business Insider. Research suggests that diets high in salt are linked to an increased risk of stomach cancer. Exercise regularly and maintain a healthy weightBeing physically active for at least 30 minutes daily can help prevent cancer, Parekh said.
Persons: , Tejal Parekh, dietitian, Parekh, Parekh it's Organizations: Service, American Cancer Society, US Centers for Disease Control, Business, International Agency for Research, Cancer, Research, CDC, Health Organization, National Cancer Institute
NOVA separates foods into four groups, starting with natural and minimally processed foods in the first category to ultraprocessed foods, which use industrial formulations and manufacturing techniques, in the fourth. Here are five things to know about ultraprocessed foods:Ultraprocessed foods are linked to bad health outcomesEating a lot of ultraprocessed foods isn’t healthy. We have one.”Ultraprocessed foods cause weight gainThat one randomized, controlled clinical trial showed that ultraprocessed foods actually caused people to gain weight. So, all those factors probably play a huge role in … the foods that we choose to eat in the real world.”Not all ultraprocessed foods are badSome ultraprocessed foods can provide important nutrients, such as whole wheat bread and yogurt. “Which goes to show that not all ultraprocessed foods necessarily drive this effect.”Hall’s team is conducting a new study to tease out which ultraprocessed foods are harmful and which are neutral, or even healthy.
Persons: Marion Nestle, Meg Tirrell, Paulette Goddard, Nestle, , ” Nestle, Kevin Hall, ” Hall, Tirrell, shouldn’t, you’re, we’re Organizations: CNN, University of São Paulo, NOVA, Nestle, New York University, National Institute of Diabetes, National Institutes of Health Clinical, , National Health, US Department of Agriculture, US Food and Drug Administration Locations: Brazil, Bethesda , Maryland
Dr. Florence Comite is a precision medicine doctor who specializes in healthy aging. She shared five diet tips she shares with patients to help them live longer. AdvertisementA precision medicine doctor shared with Business Insider six diet tips she gives her patients to help them live healthily for as long as possible. A separate study from 2023 found that people who ate diets rich in whole grains, nuts, and fruit lived around 10 years longer than those who consumed more red meat, processed foods, and sugary drinks. 10'000 Hours/ GettyDespite its name, the Mediterranean diet is more of an eating plan that is low in processed foods and red meat.
Persons: , Florence Comite, jittery, Dietitians Organizations: Florence Comite, Service, Business, Allied Market Research, Comite Center, Precision Medicine & Health, Nutrition Board, National Academies of Sciences Engineering, Medicine, Comite Locations: Florence, York
CNN —New analyses of the longest clinical trial yet of the weight-loss drug Wegovy are shedding light on how quickly it helps people lose weight, how long they sustain that weight loss and how safe the medicine is over four years of use. A previous clinical trial showed even greater average weight loss for Wegovy: about 15% on average over 68 weeks, compared with 2.4% for people who got a placebo. It was sustained for up to four yearsThe results showed that the 10% average weight loss for people using Wegovy was sustained for up to 208 weeks, or four years. Patients stayed on the medicine while they sustained the weight loss. Almost 23% of people on Wegovy lost at least 15% of their body weight, compared with 1.7% on a placebo.
Persons: Wegovy, , , Harlan Krumholz, Dr, Donna Ryan, Eli Lilly, wasn’t, they’d, Daniel Drucker, it’s, John Deanfield, Krumholz, Drucker, GLP, Sanjay Gupta Organizations: CNN, Yale University, Yale New Haven Hospital, drugmaker, Nordisk, Novo Nordisk, European, Obesity, Nature, Pennington Biomedical Research, University of Toronto, University College London, CNN Health Locations: Baton Rouge , Louisiana, Novo
Fast Food Forever: How McHaters Lost the Culture War
  + stars: | 2024-05-12 | by ( Brian Gallagher | ) www.nytimes.com   time to read: +1 min
The camera zooms in on a large woman, sitting on a cooler at the beach. It cuts to a shirtless man, also quite large, his face blurred out. The next shot shows another overweight man, sitting on a beach towel with plastic grocery bags arrayed in front of him. Directed by and starring Morgan Spurlock, the bootstrapped, lo-fi documentary was a smash hit, grossing more than $22 million on a $65,000 budget. McDonald’s, specifically, became a symbol for the glossy hegemony of American capitalism both at home and abroad.
Persons: , , Queen’s, Morgan Spurlock, Spurlock Locations: America
Donald Trump held a rally in Wildwood, New Jersey, on Saturday night. The former president launched vulgar jabs at his opponents and roused crude chants from his supporters. Trump is on trial accused of making a hush money payment to the porn star Stormy Daniels in 2016. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . AdvertisementDonald Trump launched a slew of vulgar jabs at his legal and political opponents and encouraged crude chants at a rally Saturday evening in Wildwood, New Jersey.
Persons: Donald Trump, Trump, Stormy Daniels, , MAGA, Alvin Bragg, Alvin, Juan Merchan, Merchan Organizations: Service, Manhattan District, Republican, New, Business Locations: Wildwood , New Jersey
"I've been a steadfast participant in this diet culture. AdvertisementIn 1988, Oprah Winfrey appeared on her show pulling a wagon full of fat, representing the 67 pounds she had lost in four months. Now, Winfrey told the audience that she wants to support them in their shift toward self-acceptance and healthier mindsets. Oprah Winfrey discussed her history with weight loss culture during the three-hour live stream from Weight Watchers. Shortly after, the Oscar winner helmed the ABC televised special "Shame, Blame and the Weight Loss Revolution," which saw her discuss the growing popularity of weight loss drugs such as Ozempic, Mounjaro, and Wegovy.
Persons: , Oprah Winfrey, Winfrey, I've, makeovers, We've, Sima Sistani Organizations: Service, Business, WW International, National Museum of, WeightWatchers, ABC
Read previewAs a competitive bodybuilder, Mark Taylor spent decades training hard and eating a strict low-carb diet, only to miss out on the top prizes in his native Scotland. That was until he made a drastic change: Taylor started eating carbs, and lots of them, mostly in the form of potatoes. Over the previous 10 years, he has been crowned Mr. England, Mr. United Kingdom, Mr. Britain, and Mr. World. When we exercise, we deplete these glycogen stores, so eating carbs after working out replenishes them. Eating more carbs helped Taylor have more energy for his five weekly workouts, and it made his muscles feel more "full," he said.
Persons: , Mark Taylor, Taylor, Mark Taylor Carbs, Vicky McCann who'd, McCann, Vicky, carbs, Taylor isn't, I've Organizations: Service, Business, Mr, Scottish Locations: Scotland, England, United Kingdom, Britain
New York CNN —The good news is your child got into college and is preparing to enroll this fall. The bad news is that you’ve just learned the aid package your child’s school is offering is much smaller than you’d hoped. Over four years of college, students can take out a total of up to $27,000. “That’s cash-flow friendly while your child is in college,” Walker said. Also, Bogardus suggests checking to see if your state offers a tuition aid plan or subsidized loan rates for educational expenses.
Persons: you’ve, sobering, , Beth Walker, , ” Walker, they’ve, Joseph Bogardus, it’s, Bogardus, Skip, Walker, you’ll Organizations: New, New York CNN, College Board, Center for College Planning Solutions, College, , Stafford, PLUS Locations: New York, New England, Stafford
Federal authorities on Friday charged Fat Brands and its chair Andy Wiederhorn of committing a brazen scheme that netted him $47 million in bogus loans from the restaurant company that owns Fatburger, Johnny Rockets and Twin Peaks. Fat Brands, Wiederhorn and a few other people were criminally indicted by a federal grand jury in Los Angeles for wire fraud, tax evasion and other counts related to the alleged scheme. "These charges are unprecedented, unwarranted, unsubstantiated and unjust," Fat Brands counsel Brian Hennigan said in a statement. As chief executive of Fat Brands, Wiederhorn, 58, allegedly directed the company to loan its own funds to him, with no intention of ever paying the "sham" loans back, according to the indictment. He also did not report any of the so-called loans from Fat Brands as income, according to the indictment.
Persons: Andy Wiederhorn, Johnny, Brian Hennigan, Wiederhorn, overreach —, Nicola Hanna, Wiederhorn's, Thayer, Ron Roe, Rebecca Hershinger, William Amon Organizations: Brands, Johnny Rockets, U.S . Securities, Exchange Commission, Fat Brands, SEC, Fog, Wiederhorn Locations: Los Angeles, Oregon, U.S
Toby To Yan Choi left his accounting job in California to help his father run a food stall in Hong Kong. Dai pai dongs — Hong Kong's open-air stalls serving food with a no-frills approach — are disappearing. The number of dai pai dongs in all of Hong Kong has dwindled to just over 20, according to the Hong Kong Tourism Board. The braised white pepper pork hock is one of the signature dishes at Dai Lee Dai Pai Dong. AdvertisementHe's gotten married since moving to Hong Kong and plans to move back to the US if he and his wife have kids.
Persons: Toby, Yan Choi, Dai pai dongs, , Santa Barbara, Choi, Dai Lee Dai Pai Dong, pai, Hong Kong, He's, Hong Kong Dai pai dongs, Hong, sizzling woks, Agnes Chee Yan, Wei, pai dongs, Tiffany Leung, Faye Bradley, wasn't, Shawn Cai, Law Chun Chuen, Dai Lee Dai Pai, Yan Choi There's, they've, Tony Lee, Mok Wah Ho, Ales, Yan Choi He's, Betty Richardson, dongs, Chee, I'm Organizations: Service, University of California, Kong's, Hong Kong Tourism Board, China Morning Post, Young Locations: California, Hong Kong, Santa, Hong, Sham Shui, Sham, China, Shanghai
Read previewI remember when the Mediterranean diet first became one of the hottest fads in the nutrition community — all of a sudden, my Greek salads looked super appetizing to my college roommates. Now, it's been named the healthiest diet in the world for the seventh year in a row. The condiment is a Mediterranean-diet staple and an easy swap for just about any sauce. Hanasch/ShuttershockJust because you're following a Mediterranean diet doesn't mean you can't enjoy dessert. AdvertisementYou don't need to cut out dairy to enjoy the Mediterranean dietAlthough some may say the Mediterranean diet limits cheese and dairy, my family would beg to differ.
Persons: , it's, you'd, Krzysztof Slusarczyk, creamer Organizations: Service, Business Locations: Greece, Mediterranean, tangier
Eating certain types of UPFs carries a higher risk of early death than others, a new study found. AdvertisementPeople who eat a lot of ultra-processed foods are more likely to die early than those who don't, according to a study. Chan School of Public Health, told CNN that the association between UPFs and early death was "moderate" and not equally strong among all UPFs. Notably, a recent study linked UPFs to 32 health problems, including cancer, cardiovascular disease, and depression. To address these concerns, the researchers placed UPFs into nine groups to assess if some foods had a greater impact than others.
Persons: , Mingyang, Harvard T.H, UPF, Gunter Kuhnle Organizations: Service, Harvard, of Public Health, CNN, University of Reading Locations: Chan, UPFs
Freewheeling assessments of the gaming industry have attracted millions of fans to the YouTube reviews of the personality nicknamed Dunkey, whose self-deprecating humor sweetens his critiques of popular video games. “Kirby is a lot like me,” he said while reviewing the pink puffball’s latest adventure. “He is a big fat guy that sucks up all the food.”“I’m just a referee on this one so you cannot get mad,” he explained in a middling review of Spider-Man 2, aware of the game’s rabid fan base. “This is an evil game made by an evil man,” he proclaimed about Elden Ring’s difficulty. “And whoever’s job it was to balance the damage-scaling on enemies did not show up for work.”
Persons: Dunkey, “ Kirby, ,
“I was depressed, severely depressed for that whole time.”Five months earlier, in October 2022, Bentley had started taking Mounjaro for weight loss. Ozempic uses the active ingredient semaglutide, and Wegovy is the version approved for weight loss. Mounjaro uses tirzepatide, which also targets a second hormone called GIP, and Zepbound is its brand name for weight loss. Safety in pregnancyEven as GLP-1 medicines may increase fertility, little is known about their safety during pregnancy. “It’s kind of like heart failure or sleep apnea,” he said, referring to conditions for which GLP-1 drugs have recently shown positive results.
Persons: CNN — Catera Bentley, Bentley, , , ” Bentley, she’d, , , ’ Bentley, Jody Dushay, Dushay, Catera Bentley, Ivy, Daniel Drucker, ” Drucker, they’re, Drucker, Eli Lilly, ” Dushay, haven’t, That’s, Anuja Dokras, Dokras, Melanie Cree, Cree, PCOS, aren’t, Eli Lilly’s, Daniel Skovronsky, ” Skovronsky, Dr, Sanjay Gupta, it’s, Mounjaro Organizations: CNN, Beth Israel Deaconess Medical Center, Harvard Medical School, University of, Mount Sinai, Novo Nordisk, Zepbound, US Centers for Disease Control, University of Pennsylvania, PCOS, Children’s Hospital, National Institutes of Health, CNN Health Locations: Steele , Alabama, Mount, United States, Children’s Hospital Colorado, , Colorado
Amgen is among the leaders of a pack of drugmakers racing to join the market with their own weight loss treatments. Amgen's drug, MariTide, is taken less frequently than Novo Nordisk's Wegovy and Eli Lilly's Zepbound, and may cause longer-lasting weight loss than the market leaders' injections. Novo Nordisk and Eli Lilly are also working on new weight loss drugs. The competition for a slice of the weight loss market has only grown more fierce in recent months. An injection pen of Zepbound, Eli Lilly’s weight loss drug, is displayed in New York City, U.S., December 11, 2023.
Persons: NOVO.B, Scott Olson, Eli Lilly, Nordisk's Wegovy, Eli Lilly's Zepbound, Amgen, William Blair, Matt Phipps, Bob Bradley, Boehringer Ingelheim, Phipps, Zepbound, Chris Schott, MariTide, Mario Tama, he's, Eli Lilly drugs, CagriSema, Eli Lilly’s, Brendan McDermid, Boehringer, Ingelheim, survodutide, Pascal Soriot, Christopher Furlong, dealmaking, David Denton Organizations: New, Halstead Pharmacy, Getty, Novo Nordisk, Nordisk's, William Blair & Company, CNBC, Therapeutics, AstraZeneca, Zealand Pharma, MariTide, Reuters, GLP, Pfizer, Eccogene Locations: Chicago , Illinois, Novo, Amgen, Thousand Oaks , California, New York City, U.S, Zealand, Macclesfield
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